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Unlocking New E3 Ligases for Targeted Protein Degradation in Cancer Therapy

Case Study

Posted on Sep 06, 2024

Driving circRNA Analysis with Strand’s Solutions

Case Study

Posted on Aug 01, 2024

Streamlining Germline Testing: Pipeline Development and Clinical Variant Interpretation

Case Study

Posted on Jul 17, 2024

Comprehensive End-to-End Solutions for a Pet NGS Diagnostic

Case Study

Posted on Jul 16, 2024

Workflow Management Systems: Our Software Solutions using Nextflow and Snakemake

Case Study

Posted on Mar 29, 2024

Strand-Agilent Mass Profiler Professional

Case Study

Posted on Mar 29, 2024

Spatial Transcriptomics: Our Path to 10X Genomics Visium Certification

Case Study

Posted on Mar 29, 2024

Somatic Variant Database Curation

Case Study

Posted on Mar 29, 2024

Ground Truth Dataset Curation for a Major Diagnostics Company

Case Study

Posted on Mar 29, 2024

Data Harmonization for a Big Pharmaceutical Company

Case Study

Posted on Mar 29, 2024

A Saliva-based Liquid Biopsy Assay for Oral Cancer

Case Study

Posted on Mar 29, 2024

Strand's qPCR Reporting Software

Case Study

Posted on Mar 29, 2024

Provider Portal & Electronic Data Capture Portal

Case Study

Posted on Mar 29, 2024

NGS Analysis Pipeline Development

Case Study

Posted on Mar 29, 2024

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Featured
Publications

Clinical Chemistry

Aug 2021

Determining Cost-Optimal Next-Generation Sequencing Panels for Rare Disease and Pharmacogenomics Testing

Multi-gene panel sequencing using next-generation sequencing (NGS) methods is a key tool for genomic medicine. However, with an estimated 140,000 genomic tests available, current system inefficiencies result in high genetic-testing costs.

BMC Medical Genomics

Apr 2021

Validation of whole genome sequencing from dried blood spots

Dried blood spots (DBS) are a relatively inexpensive source of nucleic acids and are easy to collect, transport, and store in large-scale field surveys, especially in resource-limited settings. However, their performance in whole-genome sequencing (WGS) relative to that of venous blood DNA has not been analyzed for various downstream applications.

Cancer Medicine

Sep 2018

Analysis of solid tumor mutation profiles in liquid biopsy

Liquid biopsy is increasingly gaining traction as an alternative to invasive solid tumor biopsies for prognosis, treatment decisions, and disease monitoring. Matched tumor-plasma samples were collected from 180 patients across different cancers with >90% of the samples below Stage IIIB.

Breast Cancer Research and Treatment

Feb 2018

Screening of over 1000 Indian patients with breast and/or ovarian cancer with a multi-gene panel: prevalence of BRCA1/2 and non-BRCA mutations

Breast and/or ovarian cancers are among the most common cancers in women across the world. In the Indian population, the healthcare burden of breast and/or ovarian cancers has been steadily rising, thus stressing the need for early detection, surveillance, and disease management measures. However, the burden attributable to inherited mutations is not well characterized.

Cancer Medicine

Apr 2017

StrandAdvantage test for early-line and advanced-stage treatment decisions in solid tumors

Comprehensive genetic profiling of tumors using next-generation sequencing (NGS) is gaining acceptance for guiding treatment decisions in cancer care. We designed a cancer profiling test combining both deep sequencing and immunohistochemistry (IHC) of relevant cancer targets to aid therapy choices in both standard-of-care (SOC) and advanced-stage treatments for solid tumors.

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